Type VI collagen is composed of a 200 kd subunit and two 140 kd subunits.
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چکیده
منابع مشابه
150-kD von Willebrand factor binding protein extracted from human vascular subendothelium is type VI collagen.
We have previously shown that von Willebrand factor (vWF), a glycoprotein which plays a critical role in the adhesion of platelets to injured blood vessels, is present within vascular subendothelium. We investigated the identity of the subendothelial binding site(s) for vWF by examining vWF binding to subendothelial constituents and solubilized a 150-kD protein with SDS-urea that bound vWF. Thi...
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چکیده ندارد.
Translatable mRNA for GP140 (a subunit of type VI collagen) is absent in SV40 transformed fibroblasts
Production of GP140, a major component of the extracellular matrix of cultured fibroblasts, is markedly decreased in SV40 transformed cells as compared with normal cells (Carter, W. G., 1982, J. Biol. Chem., 257:13805-13815). To determine at what step the biosynthesis is inhibited, we compared the levels of functional mRNA for GP140 in normal and transformed fibroblasts. Translation of total RN...
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ژورنال
عنوان ژورنال: The EMBO Journal
سال: 1986
ISSN: 0261-4189
DOI: 10.1002/j.1460-2075.1986.tb04573.x